Gene Therapy Study Published
We leverage gene therapy (blue spots) to treat myocardial infarction (brown region) via catheter-mediated direct injection of the heart.
Our preclinical gene therapy studies in pigs reveal that targeting the Hippo Kinase pathway, a “stop growth” gene network, in failing hearts is a promising strategy for promoting tissue repair and functional recovery during heart failure in humans. This work was published in Science Translational Medicine (2021) and has been featured in the Houston Chronicle, among other outlets. For more information, please visit the following links: